Assistant Professor

Cancer spread or metastasis is a dreaded word for any cancer patient and is the key determinant of cancer mortality or morbidity. Therapeutic approaches to treat metastatic cancers are limited due to a very complex and intricate nature of the signaling pathways that drive this process. Therefore, a better understanding of the metastatic process is probably needed to better target and treat the disease. 

We use multidisciplinary approaches in our lab to understand molecular basis of cellular metastasis especially EMT switching and cancer cell survival at distant sites. We are also interested in developing nanocomplex drug delivery systems for efficient and targeted therapies in cancer. We mostly rely on extramural grants for our research provided by funding agencies like SERB, CSIR, DBT and ICMR etc. Over the last few years our reserach has been funded by most of the funding bodies in india like UGC (2017), SERB (2018), CSIR (2020), and DBT (2022) 

Students/Scholars interested in this field of research are always welcome to apply for various positions that are available from time to time. They can also reach us at  beighm@uok.edu.in to discuss and enquire about possible reearch positions.

Faculty Details

  • Citations 649
  • HIndex 11
  • i10 Index 13
  • Email beighm@uok.edu.in



Research Papers Published

  • "Hydrophilically modified poly (vinylidene fluoride) nanofibers incorporating cellulose acetate fabricated by colloidal electrospinning for future tissue-regeneration applications." Polymer composites, 0(0): DOI No. 0 {ISSN: 1548-0569.} Impact Factor= 2.324
  • "Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer" European journal of cancer prevention, 0(0): 0 -0 {ISSN: 0959-8278} Impact Factor= 3.031
  • "SIX1 transcription factor: A review of cellular functions and regulatory dynamics" International Journal of Biological Macromolecules, 193(0): 1151 -1164 {ISSN: 0141-8130} Impact Factor= 8.025
  • "TGF-ß signaling: A recap of SMAD-independent and SMAD-dependent pathways" Journal of Cellular Physiology, 237(1): 59 -85 {ISSN: 0021-9541} Impact Factor= 6.384

Books Published

  • "Scaffolds fabricated from natural polymeric/composites by electrospinning for bone tissue regeneration". Springer. {ISBN: 978-981-13-0947-2} pp 32

Research Projects Details:

Title of the ProjectFunding AgencyDatedAmount (in Rs.)
Regulatory dynamics of Grainyhead like 2 proteins (GRHL2): Implications in epithelial –mesenchymal transitionUGC04-12-20171,000,000.00
Facile nano-engineered polyurethane nanofibers incorporating titanium dioxide (TiO2) and silver (Ag) nanoparticles towards guided bone tissue-regeneration.SERB, DST10-03-20174,105,470.00
Nano-bio approach for tissue-engineered antimicrobial and wound healing Polyurethane nanofibers incorporating silver nanoparticles and essential oil lavender: fabrication and comparative studyDST, Nanomission06-03-20173,590,745.00
Phospho regulatory dynamics of Sine Oculis homeobox 1 (SIX1): Implications in generation of mesenchymal phenotypeSERB25-10-20184,668,200.00
Structural insights into the mechanism of Phosphoregulation of the Grainyhead like 2 proteins: Implications in breast cancer pathogenesis.CSIR, Govt. of India13-07-20212,800,000.00
Evaluation of GSK3ß/CK2/Six1 signaling axis as a potential therapeutic node in cancer metastasisDBT, GOI31-12-20225,523,000.00